Sodium Tetradecyl Sulfate (STS)

• A sclerosing solution
• A detergent solution (the three categories of sclerosing agents are: detergent, osmotic, or chemical)
• Brands are Sotradecol and Fibro-Vein

Mechanism of action of Sodium Tetradecyl Sulfate

• Endothelial damage is dependent on concentration
• Occurs immediately after injection
• Results in rapid thrombus formation
• Ideal concentrations depend on vessel diameter, rate of blood flow, and anatomic region.
   

Patient Pre-Sclerotherapy Instructions

Before your Appointment

• Do NOT take aspirin or other blood thinning drugs (Vitamin E, Gingko Bilboa), ibuprofen, or other non-stedoid inflammatory drugs (Arthritis Medication, etc.) for 2 days before and 2 days after your treatment because these medications can increase bruising.
• If you take birth control pills or estrogen, inform the sclerotherapist about it.
• We recommend not to drink alcoholic beverages and not to smoke for 2 days before and 2 days after your treatment because drinking alcohol and smoking may impair healing.
• Do Not apply any cream, lotion, oil, or self-tanners to your legs the night before or the day of your treatment.
• Eat a light meal or snack 1 1/2 hours before your appointment.
• Bring loose fitting shorts or a leotard to wear during the treatment and long skirt or long loose fitting slacks to wear after the treatment.
• It is advised when having treatment of Reticular Veins to postpone flying for 48 hours.

Medication History
(May affect the outcome of sclerotherapy)

• Aspirin
• Vitamin E/Gingko/St. John's Wort
• Anticoagulants
• NSAIDS, ie., Motrin, Aleve, Advil, ibuprofen
• Corticosteroids
• Hormones (Estrogen can cause Post Inflammatory Hyperpigmentation)
• Use of birth control pills
• Mynocycline
• Iron (Avoid Iron one month before and after treatments if possible)

Relative Contraindications

• Acute Superficial Thrombophlebitis (how long ago)
• Severe Obesity
• Elderly
• NIDDM

Absolute Contraindications

• Pregnancy
• Advanced Collagen Vascular Disease
• Crippling Osteoarthritis - inability to walk
• Acute deep venous thrombophlebitis (DVT)
• Acute febrile illness
• Anticoagulant therapy
• Severe Bronchial Asthma (how bad, last episode, last hospitalization?)
• Debilitated Individuals
• IDDM
• Steroids
• Disulfiram (antabuse) - should not use POL or Sclerodex since these solutions contain ethyl alcohol
• Tamoxifen - may cause extensive superficial phlebitis

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